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Select item 60103421.

SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity

Wenke Wang, Amaresh Chaturbedi, Minghui Wang, Serim An, Satheeja Santhi Velayudhan, Siu Sylvia Lee

eLife. 2018; 7: e34970. Published online 2018 May 1. doi: 10.7554/eLife.34970

PMCID:: PMC6010342

Abstract Article PDF–4.4M

Select item 96793982.

Thirty years of SET/TAF1β/I2PP2A: from the identification of the biological functions to its implications in cancer and Alzheimer’s disease

Antonella Di Mambro, Maria Teresa Esposito

Biosci Rep. 2022 Nov 30; 42(11): BSR20221280. Published online 2022 Nov 21. doi: 10.1042/BSR20221280

PMCID:: PMC9679398

Abstract Article PDF–5.0M

Select item 108166993.

PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells

He Xu, Di Wu, Mingming Xiao, Yubin Lei, Yalan Lei, Xianjun Yu, Si Shi

Sci Adv. 2024 Jan 26; 10(4): eadk6633. Published online 2024 Jan 26. doi: 10.1126/sciadv.adk6633

PMCID:: PMC10816699

Abstract Article PDF–2.6M

Select item 59428544.

A Caenorhabditis elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility

Christoph G. Engert, Rita Droste, Alexander van Oudenaarden, H. Robert Horvitz

PLoS Genet. 2018 Apr; 14(4): e1007295. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007295

PMCID:: PMC5942854

Abstract Article PDF–16M

Select item 108671095.

Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis

Wenbin Xu, Han Yao, Zhen Wu, Xiaojun Yan, Zishan Jiao, Yajing Liu, Meng Zhang, Donglai Wang

Nat Commun. 2024; 15: 1362. Published online 2024 Feb 14. doi: 10.1038/s41467-024-45585-5

PMCID:: PMC10867109

Abstract Article PDF–8.0M

Select item 60634256.

GnRH regulates the expression of its receptor accessory protein SET in pituitary gonadotropes

Charlotte Avet, Chantal Denoyelle, David L’Hôte, Florence Petit, Céline J. Guigon, Joëlle Cohen-Tannoudji, Violaine Simon

PLoS One. 2018; 13(7): e0201494. Published online 2018 Jul 27. doi: 10.1371/journal.pone.0201494

PMCID:: PMC6063425

Abstract Article PDF–3.0M

Select item 99744957.

The SET oncoprotein promotes estrogen-induced transcription by facilitating establishment of active chromatin

Changying Guo, Karla F. Meza-Sosa, David Valle-Garcia, Guomeng Zhao, Kun Gao, Liting Yu, Hongying Zhang, Yeqing Chen, Liang Sun, Shira Rockowitz, Shouyu Wang, Sheng Jiang, Judy Lieberman

Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2206878120. Published online 2023 Feb 15. doi: 10.1073/pnas.2206878120

PMCID:: PMC9974495

Abstract Article PDF–1.6M

Select item 92712218.

TWO-SIGMA-G: a new competitive gene set testing framework for scRNA-seq data accounting for inter-gene and cell–cell correlation

Eric Van Buren, Ming Hu, Liang Cheng, John Wrobel, Kirk Wilhelmsen, Lishan Su, Yun Li, Di Wu

Brief Bioinform. 2022 May; 23(3): bbac084. Published online 2022 Mar 24. doi: 10.1093/bib/bbac084

PMCID:: PMC9271221

Abstract Article PDF–2.3M

Select item 56202289.

SET contributes to the epithelial-mesenchymal transition of pancreatic cancer

Hardik R. Mody, Sau Wai Hung, Kineta Naidu, Haesung Lee, Caitlin A. Gilbert, Toan Thanh Hoang, Rakesh K. Pathak, Radhika Manoharan, Shanmugam Muruganandan, Rajgopal Govindarajan

Oncotarget. 2017 Sep 15; 8(40): 67966–67979. Published online 2017 Jul 7. doi: 10.18632/oncotarget.19067

PMCID:: PMC5620228

Abstract Article PDF–5.7M

Select item 1094059510.

The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans

Felicity J. Emerson, Caitlin Chiu, Laura Y. Lin, Christian G. Riedel, Ming Zhu, Siu Sylvia Lee

Nat Commun. 2024; 15: 2320. Published online 2024 Mar 14. doi: 10.1038/s41467-024-46510-6

PMCID:: PMC10940595

Abstract Article PDF–3.5M

Select item 668373111.

SET binding to Sgo1 inhibits Sgo1–cohesin interactions and promotes chromosome segregation

Qianhui Qu, Qian Zhang, Lu Yang, Yujue Chen, Hong Liu

J Cell Biol. 2019 Aug 5; 218(8): 2514–2528. Published online 2019 Jun 21. doi: 10.1083/jcb.201810096

PMCID:: PMC6683731

Abstract Article PDF–2.7M

Select item 1005525512.

The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans

Felicity J. Emerson, Caitlin Chiu, Laura Y. Lin, Christian G. Riedel, Ming Zhu, Siu Sylvia Lee

Version 1. bioRxiv. Preprint. 2023 Mar 23. doi: 10.1101/2023.03.20.531974

Published in:: Nat Commun. 2024; 15: 2320.

PMCID:: PMC10055255

Abstract Article PDF–5.4M

Select item 593675313.

CK2 Phosphorylating I₂^PP2A/SET Mediates Tau Pathology and Cognitive Impairment

Qing Zhang, Yiyuan Xia, Yongjun Wang, Yangping Shentu, Kuan Zeng, Yacoubou A. R. Mahaman, Fang Huang, Mengjuan Wu, Dan Ke, Qun Wang, Bin Zhang, Rong Liu, Jian-Zhi Wang, Keqiang Ye, Xiaochuan Wang

Front Mol Neurosci. 2018; 11: 146. Published online 2018 Apr 30. doi: 10.3389/fnmol.2018.00146

PMCID:: PMC5936753

Abstract Article PDF–3.5M

Select item 772447414.

Embryonic Stem Cell Differentiation Is Regulated by SET through Interactions with p53 and β-Catenin

Arigela Harikumar, Patrick S.L. Lim, Malka Nissim-Rafinia, Jung Eun Park, Siu Kwan Sze, Eran Meshorer

Stem Cell Reports. 2020 Dec 8; 15(6): 1260–1274. Published online 2020 Dec 8. doi: 10.1016/j.stemcr.2020.11.004

PMCID:: PMC7724474

Abstract Article PDF–2.5M

Select item 840759315.

Multi-scale inference of genetic trait architecture using biologically annotated neural networks

Pinar Demetci, Wei Cheng, Gregory Darnell, Xiang Zhou, Sohini Ramachandran, Lorin Crawford

PLoS Genet. 2021 Aug; 17(8): e1009754. Published online 2021 Aug 19. doi: 10.1371/journal.pgen.1009754

PMCID:: PMC8407593

Abstract Article PDF–2.3M

Select item 894492116.

An Intelligent Multiattribute Decision-Support Framework Based on Parameterization of Neutrosophic Hypersoft Set

Atiqe Ur Rahman, Muhammad Saeed, Alhanouf Alburaikan, Hamiden Abd El-Wahed Khalifa

Comput Intell Neurosci. 2022; 2022: 6229947. Published online 2022 Mar 24. doi: 10.1155/2022/6229947

PMCID:: PMC8944921

Abstract Article PDF–1.0M

Select item 929373617.

PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ

Miguel Á. Casado-Combreras, Francisco Rivero-Rodríguez, Carlos A. Elena-Real, Dmitry Molodenskiy, Antonio Díaz-Quintana, Marlène Martinho, Guillaume Gerbaud, Katiuska González-Arzola, Adrián Velázquez-Campoy, Dmitri Svergun, Valérie Belle, Miguel A. De la Rosa, Irene Díaz-Moreno

Comput Struct Biotechnol J. 2022; 20: 3695–3707. Published online 2022 Jul 8. doi: 10.1016/j.csbj.2022.07.009

PMCID:: PMC9293736

Abstract Article PDF–2.8M

Select item 1070913918.

SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML

Antonella Di Mambro, Yoana Arroyo-Berdugo, Tiziana Fioretti, Michael Randles, Luca Cozzuto, Vinothini Rajeeve, Armando Cevenini, Michael J. Austin, Gabriella Esposito, Julia Ponomarenko, Claire M. Lucas, Pedro Cutillas, John Gribben, Owen Williams, Yolanda Calle, Bela Patel, Maria Teresa Esposito

Oncogene. 2023; 42(50): 3670–3683. Published online 2023 Oct 27. doi: 10.1038/s41388-023-02840-1